Physician Scientist Development Program

The Physician Scientist Development Program (PSDP) in the Department of Medicine is a post-graduate training program intended to produce clinically-trained scientists with interests ranging from basic to translational and clinically oriented research.

The program accepts qualified applicants who have completed combined MD-PhD degrees (or an MD with equivalent research experience) into a pathway that includes both medical clinical training and post doctoral research training.
Physician Scientist Development Program

PSDP Structure

Internal Medicine Residency Training: The pathway begins with clinical training in The University of Chicago’s Categorical Internal Medicine Residency Training Program. Residents benefit from exposure to complex and diverse patient populations located on the south side of Chicago in an environment that values teaching, camaraderie and a high level of resident autonomy. PSDP participants may pursue the American Board of Internal Medicine’s Research Training Pathway (i.e. “Short Track”), which allows qualified candidates to begin their sub-specialty fellowship training in lieu of their third year of residency.

Clinical Fellowship Training: PSDP participants will be given the opportunity to pursue sub-specialty training in any of The University of Chicago’s Medicine fellowships. The Department of Medicine has 11 nationally recognized ACGME accredited clinical fellowships including fellowships in Cardiology, Interventional Cardiology, Electrophysiology, Endocrinology, Gastroenterology, Geriatrics, Hematology and Oncology, Infectious Disease, Nephrology, Pulmonary and Critical Care, and Rheumatology. The majority of these fellowships have well established NIH training grants. There are also a number of non-ACGME fellowship training opportunities in areas ranging from general medicine and hospitalist medicine to ethics.

Post-Doctoral Research: Trainees are given great flexibility in their selection of laboratories and mentors for their post-doctoral research fellowship. Trainees may choose to pursue research within the Department of Medicine or take advantage of a host of opportunities located throughout the University. The University of Chicago is the home to a number of world-class research centers including the Ben May Department for Cancer Research, the University of Chicago Comprehensive Cancer Center, the Gwen Knapp Center for Lupus & Immunology Research, The University of Chicago Institute for Cardiovascular Research, the Institute for Biophysical Dynamics, the MacLean Center for Medical Ethics, the Regional Center of Excellence for Biodefense and Emerging Infectious Diseases and a Howard Hughes Medical Institute Research Center.

Transition to Junior Faculty Position: Trainees who apply for an external career development grant award in the final year of their fellowship will be given consideration for “bridge” funding to a faculty position in their respective section.


During the first two years of the program, trainees enter a formal mentorship program that encourages participation in journal club and laboratory meetings. In addition, residents meet regularly with a senior physician scientist of their choice to explore career paths and potential areas of interest. A PSDP trainee may (but is not required to) pursue the American Board of Internal Medicine’s Research Pathway (ie. “Short Track”) as long as the trainee complies with requirements as outlined by the ABIM AND maintains training evaluations at a level of “high satisfactory” or better.

Trainees are invited to attend a regular seminar series in areas of interest. These seminars include the Molecular Medicine Seminar program, the Immunology series, the Molecular Biosciences Seminar Series, and Seminar series from each Section within the Department of Medicine.

Additional support

Trainees within the PSDP are guaranteed stipend support for residency and fellowship training. Throughout the entire length of the program, the trainees receive additional financial resources to support their educational needs:

PGY1 / PGY2: During internship and the junior year of residency, trainees will receive educational funding of $5000 / year to support the purchase of computers, software, journal subscriptions and scientific conference registration.

Clinical Fellowship: During the year(s) of clinical fellowship training, trainees will receive educational funding of $5000 / year to support the purchase of computers, software, journal subscriptions and scientific conference registration.

Research Fellowship Years: During research years trainees will receive a $25,000 / year supplement to their salary, and $5000 / year to support scientific conference attendance.
Physician Scientist Development Program

Application process

  • Candidates should apply to the Physician Scientist Development Program for Internal Medicine through ERAS. Eligible candidates must have an MD-PhD or an MD with a strong background in research. They must also meet eligibility requirements for the University of Chicago’s Categorical Internal Medicine Residency Training Program.
  • A letter of recommendation from the candidate’s PhD mentor or research supervisor is required.
  • The supplemental application form should be sent to address outlined below.
  • Candidates invited to interview for a position within the PSDP will have an extended interview day, meeting with clinicians, basic researchers, and physician scientists at the University of Chicago.
  • Candidates will be evaluated on the strengths of both their clinical performance during medical school as well as their research experience and accomplishments.
  • Following their interview day, candidates will be notified of their acceptance into the PSDP should they match into the University of Chicago Internal Medicine Residency Training program.

For more information

Sonia Kupfer, MD

Associate Professor of Medicine Director, GI Cancer Risk and Prevention Clinic University of Chicago Medicine

Yun Fang, PhD

Associate Professor of Medicine, Pulmonary/Critical Care